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Working together: Heterotypic clusters and collective cell migration in melanoma metastasis.

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In this issue of Developmental Cell, Campbell et al. (2021) show that melanoma cells with distinct invasive or proliferative gene signatures can form heterotypic clusters that extravasate collectively and readily seed… Click to show full abstract

In this issue of Developmental Cell, Campbell et al. (2021) show that melanoma cells with distinct invasive or proliferative gene signatures can form heterotypic clusters that extravasate collectively and readily seed the growth of metastatic lesions. These findings highlight interactions between heterogenous tumor cells as being critical for metastasis.

Keywords: melanoma; working together; metastasis; together heterotypic; heterotypic clusters; cell

Journal Title: Developmental cell
Year Published: 2021

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