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Association between intake of white rice and incident type 2 diabetes - an updated meta-analysis.

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AIMS Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results.… Click to show full abstract

AIMS Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results. We aimed to examine the rice-T2D association in Asian populations in an updated meta-analysis. METHODS We systematically searched the Medline and Embase databases between January 2012 (the date of the first meta-analysis) and December 2020 for prospective studies examining T2D risk and baseline rice intake. Random-effects models were applied to pool relative risks (RRs). Meta regression analyses were used to evaluate the influence of sex. RESULTS Six articles with eleven comparisons in Asian countries were included in the current meta-analysis. A total of 12,395 incident T2D cases were ascertained from 256,818 participants. The pooled RR was 1.25 (95% confidence interval [CI]: 1.17-1.33) comparing extreme categories of rice intake with higher heterogeneity (I2 = 88%, P < 0.0001). When stratified by sex, the RR was 1.58 (1.26-1.99) among women and 1.30 (0.85-1.98) among men (P-interaction = 0.42). CONCLUSIONS A positive association between rice intake and incident T2D in Asian populations was found, especially among women.

Keywords: association; white rice; rice; meta analysis

Journal Title: Diabetes research and clinical practice
Year Published: 2021

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