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Activity of fosfomycin when tested against US contemporary bacterial isolates.

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Fosfomycin and comparators were susceptibility tested against over 2200 contemporary clinical isolates from US medical centers. Fosfomycin was active against Enterobacterales (MIC50/90, 4/16 μg/mL), including multidrug-resistant isolates. Potent activity was exhibited… Click to show full abstract

Fosfomycin and comparators were susceptibility tested against over 2200 contemporary clinical isolates from US medical centers. Fosfomycin was active against Enterobacterales (MIC50/90, 4/16 μg/mL), including multidrug-resistant isolates. Potent activity was exhibited against gram-positive organisms, including Staphylococcus aureus (MIC50/90, 4/8 μg/mL). Fosfomycin may provide a promising alternative option for treatment of infections where resistant bacteria may occur.

Keywords: contemporary bacterial; bacterial isolates; tested contemporary; activity fosfomycin; activity; fosfomycin tested

Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019

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