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Neisseria gonorrhoeae quickly develops drug resistance. Time-kill curves revealed that EDTA and TOL-463 inhibit growth similar to penicillin, ciprofloxacin, and azithromycin. Furthermore, synergistic and additive antimicrobial interactions occurred when EDTA… Click to show full abstract
Neisseria gonorrhoeae quickly develops drug resistance. Time-kill curves revealed that EDTA and TOL-463 inhibit growth similar to penicillin, ciprofloxacin, and azithromycin. Furthermore, synergistic and additive antimicrobial interactions occurred when EDTA and TOL-463 were combined with penicillin or azithromycin, respectively, suggesting that further investigations into these unconventional antimicrobials may be advantageous.
Keywords:
edta tol;
tol 463;
vitro activity;
neisseria gonorrhoeae;
activity edta
Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019
Link to full text (if available)
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Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019
Link to full text (if available)
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recommendations!