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We analyzed sequences of graSR, vraSR, walKR and rpoB genes in hVISA from Brazil. Five isolates showed mutations in at least one gene. rpoB H481N and graS T224I were the… Click to show full abstract
We analyzed sequences of graSR, vraSR, walKR and rpoB genes in hVISA from Brazil. Five isolates showed mutations in at least one gene. rpoB H481N and graS T224I were the most frequent mutations, followed by graR D148Q and walK A468T. Our study reinforces the heterogeneity of genetic patterns among hVISA.
Keywords:
mutations hvisa;
decreased susceptibility;
isolates decreased;
susceptibility vancomycin;
impact mutations;
hvisa isolates
Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019
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Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019
Link to full text (if available)
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recommendations!