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We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and… Click to show full abstract
We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and linezolid. The main mechanism of resistance to FQ was mutations in quinolone-resistance-determining-regions. Fifteen percent of Staphylococcus aureus overexpressed efflux-pump genes.
Keywords:
staphylococcus;
susceptibility;
fluoroquinolone resistance;
resistance mechanisms;
resistance
Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2020
Link to full text (if available)
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Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2020
Link to full text (if available)
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recommendations!