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Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection.

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In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance… Click to show full abstract

In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The Xpert MTB/XDR assay is a reliable, sensitive assay for tuberculosis and expanded resistance detection.

Keywords: xpert mtb; xdr assay; mtb xdr; resistance detection; detection

Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2021

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