Photo by diana_pole from unsplash
The placenta has vital roles in metabolite exchange, fetal growth, and pre-eclampsia (PE). In this review, we discuss the pathogenesis of hypertension in pregnancy (PE), focusing on four major theories… Click to show full abstract
The placenta has vital roles in metabolite exchange, fetal growth, and pre-eclampsia (PE). In this review, we discuss the pathogenesis of hypertension in pregnancy (PE), focusing on four major theories to explain PE, discussing endothelial roles in those theories. We focus in particular on the roles of nitric oxide (NO) and prostacyclin (PCI2) in placental endothelium, and propose new hypotheses for the influence and mechanisms of endothelial NO and PCI2 signaling pathways in PE.
Keywords:
views endothelial;
new views;
dysfunction gestational;
hypertension;
gestational hypertension;
endothelial dysfunction
Journal Title: Drug discovery today
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Drug discovery today
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!