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Three new water-soluble fluorescent organic nanoparticles with embedded structure: Structure-activity relationship and two-photon bio-imaging application

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Abstract Three benzothiazole-based two-photon absorption (2PA) chromophores (B1-3) were synthesized and the optical properties were investigated. The results illustrated the largest fluorescence quantum yield and effective 2PA cross-sections reached to… Click to show full abstract

Abstract Three benzothiazole-based two-photon absorption (2PA) chromophores (B1-3) were synthesized and the optical properties were investigated. The results illustrated the largest fluorescence quantum yield and effective 2PA cross-sections reached to 0.81 for compound B1 and 1013 GM for compound B3 in tetrahydrofuran solutions, respectively. Furthermore, the water-soluble fluorescent organic nanoparticles (FONs) possessing an embedded structure were prepared from the three compounds and Pluronic F127, which were successfully applied on two-photon nuclear envelope imaging.

Keywords: fluorescent organic; two photon; water soluble; structure; soluble fluorescent; organic nanoparticles

Journal Title: Dyes and Pigments
Year Published: 2018

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