Photo by nci from unsplash
Abstract We designed and synthesized a dual-responsive fluorescent probe MB-N-NAP to detect H2S and HClO simultaneously for precise cancer recognition. The probe can concurrently monitor variations in cellular concentrations of… Click to show full abstract
Abstract We designed and synthesized a dual-responsive fluorescent probe MB-N-NAP to detect H2S and HClO simultaneously for precise cancer recognition. The probe can concurrently monitor variations in cellular concentrations of H2S and HClO with a fast response (in seconds), high sensitivity (detection limits: H2S = 0.535 μM, HClO = 2.74 μM), high selectivity, and strong anti-interference. These outstanding properties of MB-N-NAP enabled us to distinguish cancer cells from normal cells successfully. More importantly, MB-N-NAP could specifically recognize liver cancer HepG2 cells from other hepatocarcinoma cells (Hep3B and Huh7), which offers great potential for the accurate cancer diagnosis.
Journal Title: Dyes and Pigments
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!