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Downregulation of PDZ Domain Containing 1 (PDZK1) is a Poor Prognostic Marker for Clear Cell Renal Cell Carcinoma

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Article history: Received 9 January 2017 Accepted 9 January 2017 Available online 12 January 2017 jacent tissue from the same patient. Furthermore, immunohistochemical analyses showed low PDZK1 protein expression was… Click to show full abstract

Article history: Received 9 January 2017 Accepted 9 January 2017 Available online 12 January 2017 jacent tissue from the same patient. Furthermore, immunohistochemical analyses showed low PDZK1 protein expression was correlated with a shorter overall survival time (p b 0.001) and could discriminate between good and poor prognosiswith AUC 0.877. PDZK1 is a 70-kDa adapter protein with four PDZ-interacting domains and is believed to regulate levels

Keywords: domain containing; downregulation pdz; january 2017; pdz; cell; pdz domain

Journal Title: EBioMedicine
Year Published: 2017

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