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Article history: Received 2 March 2017 Accepted 2 March 2017 Available online 4 March 2017 that these secreted factors derived from CAFs increased reactive oxygen species (ROS) levels in irradiated… Click to show full abstract
Article history: Received 2 March 2017 Accepted 2 March 2017 Available online 4 March 2017 that these secreted factors derived from CAFs increased reactive oxygen species (ROS) levels in irradiated cancer cells, enhancing PP2A activity and increasing autophagy accompanied by the repression of mTOR activation. Moreover, using a neutralizing antibody against IGF2 and an autophagy inhibitor, Wang and his colleagues demonstrated the possibility of targeting the autophagy pathway as a promising strategy
Keywords:
march 2017;
associated fibroblasts;
crosstalk cancer;
cancer cells;
cancer;
cancer associated
Journal Title: EBioMedicine
Year Published: 2017
Link to full text (if available)
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Journal Title: EBioMedicine
Year Published: 2017
Link to full text (if available)
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recommendations!