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Article history: Received 3 August 2017 Accepted 3 August 2017 Available online 4 August 2017 tion (Ozkazanc et al., 2016). Of note, under the control of these multiple inhibitory receptors,… Click to show full abstract
Article history: Received 3 August 2017 Accepted 3 August 2017 Available online 4 August 2017 tion (Ozkazanc et al., 2016). Of note, under the control of these multiple inhibitory receptors, the effector T cells easily become exhausted and anti-tumor immunity is diminished. Moreover, modulation of costimulatory molecules has been shown to substantially contribute to evasion from NK cell-mediated anti-leukemia immunity. The presence of PD-1 and TIM-3 indicates a fully responsive activated phenotype in NK cells
Keywords:
inhibitory alliance;
myeloid leukemia;
alliance myeloid;
august 2017;
leukemia;
tim
Journal Title: EBioMedicine
Year Published: 2017
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Journal Title: EBioMedicine
Year Published: 2017
Link to full text (if available)
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recommendations!