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Deguelin, a Novel Anti-Tumorigenic Agent in Human Esophageal Squamous Cell Carcinoma

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Article history: Received 15 November 2017 Accepted 15 November 2017 Available online 16 November 2017 example targeting Raf-1, Bcr, and Cdc25 phosphatase. Deguelin has the potential to impair 14-3-3 protein… Click to show full abstract

Article history: Received 15 November 2017 Accepted 15 November 2017 Available online 16 November 2017 example targeting Raf-1, Bcr, and Cdc25 phosphatase. Deguelin has the potential to impair 14-3-3 protein function through inhibition of Aurora B function.Deguelin can induce partial synchronization of cancer cells in the most radio-or DNA damaging agents-sensitive to G2-M phase, although it needs further work whether deguelin induced G2-M phase

Keywords: november 2017; tumorigenic agent; anti tumorigenic; novel anti; deguelin; deguelin novel

Journal Title: EBioMedicine
Year Published: 2017

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