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Pleural thymoma: Radiological and histological findings

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Epithelial thymic tumors (thymoma and thymic carcinoma) are rare neoplasms. The incidence of thymomas is estimated to be 0.15 cases per 100.000 persons/year in the USA [1] and it represents… Click to show full abstract

Epithelial thymic tumors (thymoma and thymic carcinoma) are rare neoplasms. The incidence of thymomas is estimated to be 0.15 cases per 100.000 persons/year in the USA [1] and it represents less than 1% of primary malignancies in adults. However, it remains the most common primary neoplasm of the anterior mediastinum, accounting for 20% of tumors in this location [2]. Ectopic thymomas have been described in the neck, middle mediastinum, posterior mediastinum, lung and pleura; few reports have described giant intrathoracic tumors, but they account only 4% of all thymomas [3,4]. Usually, about 70% of patients with thymomas remains asymptomatic; the rest of patients may present local symptoms related to tumor encroaching on surrounding structures like cough, chest pain, superior vena cava syndrome, dysphagia, and hoarseness of voice. Only 30% of patients with thymoma has clinic related to myasthenia gravis. An additional 5% of patients have other systemic syndromes including red cell aplasia, dermatomyositis, systemic lupus erythematous, Cushing syndrome and syndrome of inappropriate antidiuretic hormone secretion (SIHAD) [5]. The aim of this report is to describe the main radiological finding on X-ray, computed tomography (CT) and positron emission tomography (PET), in a case of pleural thymoma. We also report how perform radiological thymoma staging. 2. Case discussion

Keywords: radiological histological; pleural thymoma; thymoma radiological; histological findings; mediastinum

Journal Title: European Journal of Radiology Open
Year Published: 2018

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