Severe acute respiratory coronavirus 2 (SARS-CoV2) and the resulting acute respiratory distress syndrome (COVID-19) is responsible for a worldwide pandemic, with over 10 million cases reported as of 28th June… Click to show full abstract
Severe acute respiratory coronavirus 2 (SARS-CoV2) and the resulting acute respiratory distress syndrome (COVID-19) is responsible for a worldwide pandemic, with over 10 million cases reported as of 28th June 2020.S1 Whilst severe disease requiring hospitalisation is characterised by pneumonia and respiratory failure, a significant proportion also develop acute kidney injury (AKI). Within critical care admissions with COVID-19, 16 to 35% are reported as requiring renal replacement therapy. 2 , 3 , S2,S3 There is increasing recognition of an associated coagulopathy in hospitalised patients characterised by a prothrombotic state and increased venous thromboembolism. This brief review presents the current understanding of the coagulopathy associated with COVID-19, the risk of venous thrombosis and the impact of this on management of renal replacement therapy in critically ill patients with COVID-19.
               
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