Paraneoplastic syndromes are systemic disorders in response to a neoplasm and can have various clinical manifestations depending on the organ system(s) affected. Paraneoplastic renal cell carcinoma (RCC) arises from the… Click to show full abstract
Paraneoplastic syndromes are systemic disorders in response to a neoplasm and can have various clinical manifestations depending on the organ system(s) affected. Paraneoplastic renal cell carcinoma (RCC) arises from the release of cytokines and hormones from the tumor and can have a variety of presentations including hypertension, hypercalcemia, anemia, fevers, coagulopathy, transaminitis, and polycythemia. Approximately 10–40% of patients with RCC develop a paraneoplastic syndrome of which hypercalcemia and hypertension are among the two most common presenting signs. Paraneoplastic RCC in the perinatal period, however, is exceedingly rare. Here, we illustrate a novel clinical scenario of paraneoplastic RCC presenting in a previously healthy 20 year old postpartum patient whose pregnancy was complicated by preeclampsia and placental abruption.
               
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