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Should A Couple with Failed In Vitro Fertilization/Intracytoplasmic Sperm Injection and Increased Sperm DNA Fragmentation Use Testicular Sperm for the Next Cycle?

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Limited observational data purporting a benefit of testicular sperm for intracytoplasmic sperm injection failure do not provide sufficient evidence. The first step is to reduce sperm DNA fragmentation in ejaculated… Click to show full abstract

Limited observational data purporting a benefit of testicular sperm for intracytoplasmic sperm injection failure do not provide sufficient evidence. The first step is to reduce sperm DNA fragmentation in ejaculated sperm through lifestyle modifications, antioxidant therapy, or treatment of underlying abnormalities such as infection or varicocele.

Keywords: testicular sperm; intracytoplasmic sperm; sperm injection; sperm dna; dna fragmentation

Journal Title: European urology focus
Year Published: 2018

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