HIGHLIGHTS • Extracellular phenotype, apoptosis, or cell cycle profile at thawing cannot predict acute myeloid leukemia (AML) xenograft potential.• Leukemic long-term culture-initiating cell content distinguishes fast and delayed engraftment potential.•… Click to show full abstract
HIGHLIGHTS • Extracellular phenotype, apoptosis, or cell cycle profile at thawing cannot predict acute myeloid leukemia (AML) xenograft potential.• Leukemic long-term culture-initiating cell content distinguishes fast and delayed engraftment potential.• Defined here is a 1-week carboxyfluorescein succinimidyl ester-based assay that predicts AML xenograft success.
               
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