Abstract The zanthoxylum herbs are the dual-purpose Chinese herbal medicine and functional food favored by East and Southeast Asians. In this study, nematicidal and antibacterial major active components among ten… Click to show full abstract
Abstract The zanthoxylum herbs are the dual-purpose Chinese herbal medicine and functional food favored by East and Southeast Asians. In this study, nematicidal and antibacterial major active components among ten typical zanthoxylum herbs (ethanol extracts) were investigated comprehensively by high resolution mass spectrometry. The major ingredients and their contents were analyzed, especially summarizing the typical fragment ions of alkaloids, amides, lignans, and coumarins of zanthoxylum herbs. We found that ethanol extracts of zanthoxylum herbs showed significantly high antibacterial properties. The MICs values of Zanthoxylum piasezkii Maxim (CJ), Zanthoxylum khasianum Hook (HJ), and Zanthoxylum armatum DC (ZYHJ) with S. aureus, MRSA, S. hemolyiicus and C. albicans were 0.1–0.5 mg/mL, respectively. In addition, CJ extract (1 mg/mL) had a significant effect on killing nematode eggs (p
               
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