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Background: Advances in preimplantation genetic screening (PGS) have revolutionized the field of personalized and genomic medicine. PGS enables the clinician to select a single euploid embryo for transfer, resulting in… Click to show full abstract
Background: Advances in preimplantation genetic screening (PGS) have revolutionized the field of personalized and genomic medicine. PGS enables the clinician to select a single euploid embryo for transfer, resulting in high pregnancy rates and nearly eliminating the risk of multiple gestations. Unfortunately, PGS of embryos has not eliminated the risk of early pregnancy loss (EPL) [1]. Published research has suggested links between the incidence of biochemical pregnancies and the presence of diminished ovarian reserve [2] and/or endometrial or immune factors [3], though the precise etiology and pathophysiology remain unclear.
Journal Title: Fertility and Sterility
Year Published: 2017
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