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Serratene-type triterpenoids from Palhinhaea cernua.

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Phytochemical investigation of the 95% ethanol extract of the whole plant of Palhinhaea cernua afforded five new serratene-type triterpenoids (1-5) together with four known analogues (6-9). The structures of the… Click to show full abstract

Phytochemical investigation of the 95% ethanol extract of the whole plant of Palhinhaea cernua afforded five new serratene-type triterpenoids (1-5) together with four known analogues (6-9). The structures of the new compounds were elucidated by extensive spectroscopic analysis and X-ray crystallographic data. Compounds 1-3 triggered apoptosis of Hela-/- cell with EC50 values of 3.49 ± 0.05, 0.28 ± 0.13 and 7.98 ± 0.03 μM, respectively.

Keywords: serratene type; triterpenoids palhinhaea; palhinhaea cernua; type triterpenoids

Journal Title: Fitoterapia
Year Published: 2018

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