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Acylphloroglucinol derivatives from the leaves of Syzygium samarangense and their cytotoxic activities.

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Samarones A-D (1-4), four new acylphloroglucinol derivatives bearing a C17 alkyl side chain, along with five known analogues (5-9), were isolated from the leaves of Syzygium samarangense. Their structures were… Click to show full abstract

Samarones A-D (1-4), four new acylphloroglucinol derivatives bearing a C17 alkyl side chain, along with five known analogues (5-9), were isolated from the leaves of Syzygium samarangense. Their structures were characterized on the basis of extensive spectroscopic methods including HR-ESI-MS/MS analysis. The cytotoxic activities of compounds 1-3 and 5-9 against HepG2 and MDA-MB-231 cells were also evaluated.

Keywords: cytotoxic activities; syzygium samarangense; leaves syzygium; acylphloroglucinol derivatives

Journal Title: Fitoterapia
Year Published: 2018

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