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Five novel globoscinic acid derivatives, aspergilates A-E (1-5) have been isolated from endophytic fungus Aspergillus sp. derived from Paeonia ostii. The structures of aspergilates A-E were determined by in-depth analyses… Click to show full abstract
Five novel globoscinic acid derivatives, aspergilates A-E (1-5) have been isolated from endophytic fungus Aspergillus sp. derived from Paeonia ostii. The structures of aspergilates A-E were determined by in-depth analyses of NMR spectra, HRESIMS and CD experiments. The absolute configurations of compounds 2-5 were determined by the ECD calculations based on quantum chemistry. Cytotoxic activities against five selected tested tumor cell lines of 1-5 were evaluated.
Keywords:
paeonia ostii;
isolated paeonia;
metabolites aspergillus;
aspergilates second;
aspergillus isolated;
second metabolites
Journal Title: Fitoterapia
Year Published: 2018
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Journal Title: Fitoterapia
Year Published: 2018
Link to full text (if available)
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recommendations!