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A new sesquiterpene glycoside and a new amide have been isolated from the stems of Tinospora sinensis. Their structures were established by 2D NMR spectroscopic techniques (1H,1H-COSY, NOESY, HSQC and… Click to show full abstract
A new sesquiterpene glycoside and a new amide have been isolated from the stems of Tinospora sinensis. Their structures were established by 2D NMR spectroscopic techniques (1H,1H-COSY, NOESY, HSQC and HMBC) and mass spectrometry. The isolated compounds were subjected to evaluate neuroprotective activities in vitro. The pre-treatment of two new compounds can significantly ameliorate damage of oxidative stress induced by Aβ25-35 and improve PC12 cells survival.
Keywords:
glycoside phenylalanine;
tinospora sinensis;
sesquiterpene glycoside;
phenylalanine derivatives
Journal Title: Fitoterapia
Year Published: 2019
Link to full text (if available)
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Journal Title: Fitoterapia
Year Published: 2019
Link to full text (if available)
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recommendations!