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Three new homoadamantane-type polyprenylated acylphloroglucinols, hyperacmosins E-G (1-3), with seven known compounds were isolated from the air-dried aerial parts of Hypericum asmosepalum. Their structures were determined by NMR, HRESIMS and… Click to show full abstract
Three new homoadamantane-type polyprenylated acylphloroglucinols, hyperacmosins E-G (1-3), with seven known compounds were isolated from the air-dried aerial parts of Hypericum asmosepalum. Their structures were determined by NMR, HRESIMS and experimental electronic circular dichroism (ECD) spectra. The hepatoprotective activity of these compounds were evaluated. Compounds 4 and 8 exhibited hepatoprotective activity against paracetamol-induced HepG2 cell damage.
Keywords:
type polyprenylated;
homoadamantane type;
new homoadamantane;
three new;
polyprenylated acylphloroglucinols
Journal Title: Fitoterapia
Year Published: 2020
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Journal Title: Fitoterapia
Year Published: 2020
Link to full text (if available)
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recommendations!