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Six new cadinane-type sesquiterpenoids, named Chimnitensin A-F (1-6) were isolated from the leaves of Chimonanthus nitens Oliv. Their structures were elucidated by comprehensive spectroscopic analyses and comparison with structurally related… Click to show full abstract
Six new cadinane-type sesquiterpenoids, named Chimnitensin A-F (1-6) were isolated from the leaves of Chimonanthus nitens Oliv. Their structures were elucidated by comprehensive spectroscopic analyses and comparison with structurally related known analogues. In vitro MTT assay showed that all six compounds had cytotoxicity against two selected human breast cancer cell lines (MDA-MB-468 and MDA-MB-231), which indicate their potential of developing into anticancer drugs.
Keywords:
leaves chimonanthus;
type sesquiterpenoids;
six new;
chimonanthus nitens;
new cadinane;
cadinane type
Journal Title: Fitoterapia
Year Published: 2021
Link to full text (if available)
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Journal Title: Fitoterapia
Year Published: 2021
Link to full text (if available)
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recommendations!