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An investigation on the extract from the plant Trichilia sinensis Bentv. led to the isolation of 13 new limonoids (1-13), in which two were of khayalactone skeleton and 11 were… Click to show full abstract
An investigation on the extract from the plant Trichilia sinensis Bentv. led to the isolation of 13 new limonoids (1-13), in which two were of khayalactone skeleton and 11 were phragmalin-type limonoids, and eight known phragmalin-type limonoids (14-21). Their structures were elucidated by using spectroscopic techniques and HRESIMS experiment. Compounds 6 and 17 displayed potent protein tyrosine phosphatase 1B inhibitory activity with IC50 values of 1.2 ± 0.1 and 8.1 ± 0.5 μM, respectively.
Keywords:
trichilia sinensis;
type limonoids;
sinensis bentv;
phragmalin type
Journal Title: Fitoterapia
Year Published: 2021
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Journal Title: Fitoterapia
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!