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Fabrication and characterization of protein-phenolic conjugate nanoparticles for co-delivery of curcumin and resveratrol

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Abstract Curcumin and resveratrol are polyphenols widely used as nutraceuticals because of their strong antioxidant activities and potential health benefits. In this study, the possibility of improving their water-dispersibility, chemical… Click to show full abstract

Abstract Curcumin and resveratrol are polyphenols widely used as nutraceuticals because of their strong antioxidant activities and potential health benefits. In this study, the possibility of improving their water-dispersibility, chemical stability, and bioaccessibility using core-shell nanoparticles was examined. The hydrophobic core was fabricated from zein-epigallocatechin gallate conjugates using an antisolvent precipitation method, while the shell was fabricated by coating the core with a biosurfactant (rhamnolipid). The yield, size, morphology, charge (ΞΆ-potential), and loading efficiency of these core-shell nanoparticles were characterized. The nanoparticles formed were anionic spheres with mean diameters

Keywords: fabrication characterization; curcumin resveratrol; characterization protein; curcumin; core

Journal Title: Food Hydrocolloids
Year Published: 2018

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