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Complex mix of psidium guajava. L as a protector of medicines used in the treatment of gastric ulcer

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Metabolic reactions that favor the production of free radicals generate oxidative stress and chain reactions, which result in illnesses such as gastritis, cancer, arthritis, etc.* Gastric ulcer is deemed as… Click to show full abstract

Metabolic reactions that favor the production of free radicals generate oxidative stress and chain reactions, which result in illnesses such as gastritis, cancer, arthritis, etc.* Gastric ulcer is deemed as an inflammatory pathology related to an infection by H. pylori, whose treatment includes tetracycline and omeprazole. Furthermore, the hypochlorous acid (HOCl) is released in the lymphocytes as immune response to inflammatory processes through in situ oxidation reactions. HOCl has been proven to degrade these medicines* and the treatment does not consider external factors that cause health problems (harmful lifestyles, stress, and environmental factors). In this context, we propose an alternative treatment to gastric ulcer based on spectroscopic and chromatographic results including the species Psidium Guajava L as gastric protector for combined treatment. This species has antioxidant properties, associated to ascorbic acid, carotenoids, and phenolic compounds*; anti-inflammatory properties thanks to flavonoids; analgesic properties due to triterpenes; and antibacterial properties because of tannins. **

Keywords: treatment gastric; psidium guajava; treatment; gastric ulcer

Journal Title: Free Radical Biology and Medicine
Year Published: 2018

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