LAUSR

INTRODUCTION Colorectal cancer (CRC) screening programs produce risks, including those derived from colorectal surgeries. The objective of this analysis is to evaluate the complications associated with the surgery. PATIENTS AND METHODS Retrospective analysis including patients who required colorectal surgery within the population-based CRC screening program in Galicia (May 2013-June 2019). We analyzed the indication for surgery and the rate of in-hospital (mild I-II, severe III-V, Clavien-Dindo classification) and at discharge complications. We performed a multivariate analysis to determine the variables independently associated. RESULTS In the analyzed period, 1092 patients underwent surgery (benign lesion 16.5%, pT1 CRC 18.2%, rest of CRC 64.6%) laparoscopic approach in 69.8% of the cases. In-hospital complications were detected in 19.2% of patients (mild: 13.4%, severe: 5.9%, deaths: 0.2%) and at discharge in 159 (14.6%) patients. Male sex was associated with in-hospital complications (OR 2.0 95% CI 1.3-3.0). The variables associated with severe complications were: male sex (OR 2.6, 95% CI 1.2-5.5), tertiary hospital (OR 0.5, 95% CI (0.2-0.9) and ECOG I (OR 0.2, 95% CI 0.05-0.6). The factors associated with complications after discharge were age ≥60 years (OR 1.5, 95% CI 1.0-2.3), rectal location (OR 1.6, 95% CI 1.1-2.3) and in-hospital complications (OR 2.2, 95% CI 1.5-3.2). CONCLUSIONS Surgery is the main cause of morbidity and mortality associated with a CRC screening program. These results must be taken into account in the decision making of lesions that are candidates for endoscopic resection.