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Successful treatment of metastatic refractory gestational choriocarcinoma with pembrolizumab: A case for immune checkpoint salvage therapy in trophoblastic tumors

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Highlights • Cure rates are high for choriocarcinoma, however chemoresistant disease often leads to death.• High expression of PD-L1 suggests a role for checkpoint inhibitors in choriocarcinoma.• Pembrolizumab should be… Click to show full abstract

Highlights • Cure rates are high for choriocarcinoma, however chemoresistant disease often leads to death.• High expression of PD-L1 suggests a role for checkpoint inhibitors in choriocarcinoma.• Pembrolizumab should be considered for salvage therapy for chemoresistant choriocarcinoma.

Keywords: choriocarcinoma pembrolizumab; salvage therapy; choriocarcinoma; checkpoint

Journal Title: Gynecologic Oncology Reports
Year Published: 2020

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