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Highlights • Neoadjuvant chemotherapy induces heterogeneous changes in the tumor microenvironment.• Macrophages are a significant component of the TME PD-L1 expression enriched in a subset of patients.• Alteration in T… Click to show full abstract
Highlights • Neoadjuvant chemotherapy induces heterogeneous changes in the tumor microenvironment.• Macrophages are a significant component of the TME PD-L1 expression enriched in a subset of patients.• Alteration in T cell ratios after chemotherapy indicate patient subsets favorable to checkpoint modulation in the recurrent setting.
Keywords:
chemotherapy immune;
chemotherapy;
impact chemotherapy;
understanding impact;
landscape high;
immune landscape
Journal Title: Gynecologic Oncology Reports
Year Published: 2022
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Journal Title: Gynecologic Oncology Reports
Year Published: 2022
Link to full text (if available)
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recommendations!