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Purpose: Elevated donor-derived cell-free DNA (dd-cfDNA) has been observed in transplant patients undergoing acute rejection, but the relationship between dd-cfDNA and long term outcomes has not previously been studied. In… Click to show full abstract
Purpose: Elevated donor-derived cell-free DNA (dd-cfDNA) has been observed in transplant patients undergoing acute rejection, but the relationship between dd-cfDNA and long term outcomes has not previously been studied. In this exploratory study, serially measured dd.cfDNA from heart transplant patients is used for predict 3-year patient adverse outcomes of death, retransplantation, hemodynamic compromise or graft dysfunction.
Keywords:
heart;
free dna;
cell free;
heart transplant;
donor derived;
derived cell
Journal Title: Journal of Heart and Lung Transplantation
Year Published: 2017
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Journal Title: Journal of Heart and Lung Transplantation
Year Published: 2017
Link to full text (if available)
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recommendations!