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Evaluating the Efficacy of Achillea Millefolium Ointment in Treatment of Recurrent Idiopathic Epistaxis; A Randomized Double-Blinded Clinical Trial

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Abstract Epistaxis is one of the most common reasons for patient referral to ear, nose and throat (ENT) clinics and reported to involve 60 % of the total population. This… Click to show full abstract

Abstract Epistaxis is one of the most common reasons for patient referral to ear, nose and throat (ENT) clinics and reported to involve 60 % of the total population. This study aimed to evaluate the efficacy of Achillea Millefolium ointment in the treatment of recurrent idiopathic epistaxis. In this randomized, double-blind, placebo-controlled, trial, fifty patients with idiopathic recurrent epistaxis completed the study. Full initial assessments and coagulation tests were performed prior to the study. The patients were randomly divided into two groups of case and control and received "Vitamin A and Achillea Ointment" or "Vitamin A and Placebo ointment" on alternate days respectively (Vitamin A ointment on day 1 and Achillea or Placebo ointment on the next day) for 10 days. Nasal examinations and coagulation tests were carried out on day 10 and patients were visited at the end of first and third month following treatment initiation. The amount of bleeding was recorded by Epistaxis Severity Score (ESS) before and after the intervention (10th Day, 1st and 3rd Month). There was no significant difference in frequency and duration of bleeding between two groups on day 10 (p = 0.105). However, a significant reduction in frequency and duration of bleeding was seen in the case group in the first and third month follow-up (p

Keywords: efficacy achillea; achillea; treatment; ointment; day; epistaxis

Journal Title: Journal of Herbal Medicine
Year Published: 2021

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