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A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone

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Key Teaching Points • Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment.… Click to show full abstract

Key Teaching Points • Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment. • Propafenone could be effective for treatment of patients with CPVT. • The beneficial effect of the monotherapy with propafenone in our patient may result from the combined antiarrhythmic effect of this drug with Na+ channel blockade and beta blocker capabilities.

Keywords: ventricular tachycardia; effective treatment; polymorphic ventricular; treatment; propafenone; catecholaminergic polymorphic

Journal Title: HeartRhythm Case Reports
Year Published: 2019

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