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Enhanced electrocardiographic monitoring of patients with Coronavirus Disease 2019

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Abstract Background Many of the drugs being used in the treatment of the ongoing pandemic coronavirus disease 2019 (COVID-19) are associated with QT prolongation. Expert guidance supports ECG monitoring to… Click to show full abstract

Abstract Background Many of the drugs being used in the treatment of the ongoing pandemic coronavirus disease 2019 (COVID-19) are associated with QT prolongation. Expert guidance supports ECG monitoring to optimize patient safety. Objective To establish an enhanced process for ECG monitoring of patients being treated for COVID-19. Methods We created an SBAR (Situation Background Assessment Recommendation Tool) identifying the indication for ECGs in COVID-19 patients, and tagged these ECGs to ensure prompt over reading and identification of those with QT prolongation (QTc >470 ms for QRS < 120 ms, QTc > 500 ms for QRS > 120 ms). This triggered a phone call from the electrophysiology service to the primary team to provide management guidance and a formal consultation if requested. Results During a 2-week period we reviewed 2006 ECGs, corresponding to 524 unique patients, of whom 103 (19.7%) met SBAR defined criteria for QT prolongation. When compared to those without QT prolongation, these patients were more often in the intensive care unit (58.3% vs 35.4%) and more likely to be intubated (31.1 vs 18.1%). Fifty patients with QT prolongation (48.5%) had electrolyte abnormalities, 98 (95.1%) were on COVID-19 related QT prolonging medications, and 62 (60.2%) were on 1-4 additional non COVID-19 related QT prolonging drugs. Electrophysiology recommendations were given to limit modifiable risk factors. No patient developed torsade de pointes. Conclusion This process functioned efficiently, identified a high percentage of patients with QT prolongation, and led to relevant interventions. Arrhythmias were rare. No patient developed torsade de pointes.

Keywords: enhanced electrocardiographic; disease 2019; monitoring; monitoring patients; coronavirus disease; prolongation

Journal Title: Heart Rhythm
Year Published: 2020

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