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Anemia with thrombocytosis in an elderly male: a case of myelodysplastic syndrome-myeloproliferative neoplasm with ringed sideroblasts and thrombocytosis

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yelodysplastic syndrome (MDS)-myeloproliferative neolasm (MPN) with ringed sideroblasts and thrombocytosis MDS/MPN-RS-T) is a rare entity categorized under the yelodysplastic-myeloproliferative group (MDS/MPN) in the ecent 2016 World Health Organization (WHO) update… Click to show full abstract

yelodysplastic syndrome (MDS)-myeloproliferative neolasm (MPN) with ringed sideroblasts and thrombocytosis MDS/MPN-RS-T) is a rare entity categorized under the yelodysplastic-myeloproliferative group (MDS/MPN) in the ecent 2016 World Health Organization (WHO) update on he classification of myeloid neoplasms.1 Initially named s refractory anemia with ringed sideroblasts associated ith marked thrombocytosis (RARS-T), it was a provisional ntity under MDS/MPN in the 2008 WHO classification of ematopoietic tumors. Patients with this condition have linico-morphological features of MDS (RARS) along with arked thrombocytosis and abnormal megakaryocytes simiar to those seen in breakpoint cluster region-Abelson murine eukemia-1 (BCR ABL1)-negative MPN.

Keywords: anemia; thrombocytosis; mpn; ringed sideroblasts; syndrome; sideroblasts thrombocytosis

Journal Title: Hematology, Transfusion and Cell Therapy
Year Published: 2018

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