Photo from wikipedia
Highlights • We exposed astrocytes to Aβ 25-35 and then co-cultured them with primary hippocampal neurons.• The Aβ25-35-exposed astrocytes lowered excitatory postsynaptic release and the size of the readily releasable… Click to show full abstract
Highlights • We exposed astrocytes to Aβ 25-35 and then co-cultured them with primary hippocampal neurons.• The Aβ25-35-exposed astrocytes lowered excitatory postsynaptic release and the size of the readily releasable synaptic pool.• The number of excitatory synapses was reduced by direct contact between Aβ25-35-exposed astrocytes and hippocampal neurons.• The dendritic branching was decreased by direct contact between Aβ25-35-exposed astrocytes and hippocampal neurons.• The number of excitatory synapses and dendrite branches were conserved by putting distance from Aβ25-35-exposed astrocytes.
Journal Title: IBRO Reports
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!