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Highlights • Extensive, ascending relaxin-3-containing neural networks are present throughout the rat forebrain.• Relaxin-3 signalling modulates complex behaviours and cognitive processes including feeding, anxiety and memory.• We tested a 1736… Click to show full abstract
Highlights • Extensive, ascending relaxin-3-containing neural networks are present throughout the rat forebrain.• Relaxin-3 signalling modulates complex behaviours and cognitive processes including feeding, anxiety and memory.• We tested a 1736 bp promoter sequence for specific transgene expression in relaxin-3 neurons of rat nucleus incertus (NI).• This promoter restricted m-Cherry marker expression to NI relaxin-3 neurons with 98% specificity.• This targeted transgene delivery offers a versatile method for ongoing preclinical studies of relaxin-3 circuitry.
Journal Title: IBRO Reports
Year Published: 2020
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