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A cautionary tale of false-negative nasopharyngeal COVID-19 testing

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Abstract There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. We present a case where two nasopharyngeal specimens were… Click to show full abstract

Abstract There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. We present a case where two nasopharyngeal specimens were negative, followed by a positive sputum sample. Serial testing for COVID-19 is indicated in patients with high pretest probability of disease.

Keywords: negative nasopharyngeal; nasopharyngeal; false negative; covid; cautionary tale; tale false

Journal Title: IDCases
Year Published: 2020

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