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BACKGROUND AND OBJECTIVES The relative bleeding risk of aspirin versus vitamin K antagonists (VKA) is unclear. Most of previous meta-analyses included trials with target INR for VKA therapy far beyond… Click to show full abstract
BACKGROUND AND OBJECTIVES
The relative bleeding risk of aspirin versus vitamin K antagonists (VKA) is unclear. Most of previous meta-analyses included trials with target INR for VKA therapy far beyond usually recommended range (2-3). The aim of this study was to compare the bleeding risk of aspirin and VKA, as indicated by the aggregate body of clinical evidence including data from the recently published WARCEF trial.
METHODS
In this meta-analysis we included randomized controlled trials that compared aspirin to VKA (1.4
Journal Title: International journal of cardiology
Year Published: 2017
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