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Trimetazidine (TMZ) has traditionally been used as an anti-ischemic drug for coronary artery disease by selectively inhibiting the mitochondrial long-chain 3-ketoacyl-CoA thiolase. Recently, new applications for this therapy have been… Click to show full abstract
Trimetazidine (TMZ) has traditionally been used as an anti-ischemic drug for coronary artery disease by selectively inhibiting the mitochondrial long-chain 3-ketoacyl-CoA thiolase. Recently, new applications for this therapy have been investigated. This article reviews alternative uses for TMZ in non-coronary artery diseases, such as non-ischemic cardiomyopathy, sepsis, myocardial dysfunction induced by anti-cancer drugs, diabetic cardiomyopathy and contrast-induced nephropathy.
Keywords:
trimetazidine conditions;
conditions coronary;
disease;
drug;
coronary disease;
disease old
Journal Title: International journal of cardiology
Year Published: 2017
Link to full text (if available)
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Journal Title: International journal of cardiology
Year Published: 2017
Link to full text (if available)
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recommendations!