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Repeated neonatal needle-prick stimulation increases inflammatory mechanical hypersensitivity in adult rats

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Newborn infants are vulnerable to procedural stress and pain exposure on the first weeks of life that represents a critical period for the development of nociceptive, sensory, emotional, and social… Click to show full abstract

Newborn infants are vulnerable to procedural stress and pain exposure on the first weeks of life that represents a critical period for the development of nociceptive, sensory, emotional, and social functions. We evaluated the nociceptive behavior of adult male and female rats that were submitted to nociceptive experience in the neonatal period and the maternal behavior in the postnatal period.

Keywords: adult; stimulation increases; prick stimulation; needle prick; repeated neonatal; neonatal needle

Journal Title: International Journal of Developmental Neuroscience
Year Published: 2019

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