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High prevalence of epilepsy in an onchocerciasis endemic health zone in the Democratic Republic of the Congo, despite 14 years of community-directed treatment with ivermectin: A mixed-method assessment

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Highlights • A high epilepsy prevalence in the Aketi health zone was observed despite 14 years of community-directed treatment with ivermectin.• The high prevalence of OV16 antibodies in children is… Click to show full abstract

Highlights • A high epilepsy prevalence in the Aketi health zone was observed despite 14 years of community-directed treatment with ivermectin.• The high prevalence of OV16 antibodies in children is indicative of high ongoing onchocerciasis transmission.• High onchocerciasis transmission is the consequence of high exposure to blackflies and low intake of ivermectin.• Head nodding seizures were observed in 13.8% of the persons with epilepsy.• Ivermectin coverage needs to be increased and bi-annual distribution should be considered.

Keywords: despite years; community directed; prevalence; years community; health zone; onchocerciasis

Journal Title: International Journal of Infectious Diseases
Year Published: 2019

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