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In this study, a "click and hybridization" strategy was developed for the functionalization of polydiacetylene micelles with a targeting aptamer ligand. Decoration of the nanocarriers with an anti-Annexin A2 sequence… Click to show full abstract
In this study, a "click and hybridization" strategy was developed for the functionalization of polydiacetylene micelles with a targeting aptamer ligand. Decoration of the nanocarriers with an anti-Annexin A2 sequence efficiently triggered enhanced internalization of the functionalized micelles in the MCF-7 cell line, with a marked increase compared to control micelles.
Keywords:
improved targeting;
micelles improved;
decorated polydiacetylene;
aptamer decorated;
polydiacetylene;
polydiacetylene micelles
Journal Title: International journal of pharmaceutics
Year Published: 2019
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Journal Title: International journal of pharmaceutics
Year Published: 2019
Link to full text (if available)
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recommendations!