LAUSR

Highlights • Penetration of the visceral peritoneum by a mucinous neoplasm consists the cardinal point in the management and prognosis.• Patients with LAMN confined to the muscularis propria after histologic examination of the entire appendix (pTis) have essentially no risk of recurrence.• There are no clear guidelines regarding appropriate management of appendiceal LAMNs with positive margins, especially when confined within the serosa.• A simple cecectomy is traditionally suggested by some authors, but according to more recent data its necessity is debated.• LAMN may rarely recur in the form of a polypoid protrusion into the cecal lumen and this may originate from the buried stump of the appendix on the ground of a positive margin.