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Late onset hyperplastic callus formation in osteogenesis imperfecta type V simulating osteosarcoma—A case report

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Highlights • Hyperplastic callus formation is a very rare complication of osteogenesis imperfecta type V.• The most important differential diagnosis is malignant osteosarcoma.• A biopsy is the only way to… Click to show full abstract

Highlights • Hyperplastic callus formation is a very rare complication of osteogenesis imperfecta type V.• The most important differential diagnosis is malignant osteosarcoma.• A biopsy is the only way to distinguish between those two conditions.• The underlying pathophysiology is still unknown and there is no causal therapy.• A multidisciplinary approach in diagnosis and therapy is mandatory.

Keywords: hyperplastic callus; osteogenesis imperfecta; imperfecta type; callus formation

Journal Title: International Journal of Surgery Case Reports
Year Published: 2020

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