Highlights • Hyperplastic callus formation is a very rare complication of osteogenesis imperfecta type V.• The most important differential diagnosis is malignant osteosarcoma.• A biopsy is the only way to… Click to show full abstract
Highlights • Hyperplastic callus formation is a very rare complication of osteogenesis imperfecta type V.• The most important differential diagnosis is malignant osteosarcoma.• A biopsy is the only way to distinguish between those two conditions.• The underlying pathophysiology is still unknown and there is no causal therapy.• A multidisciplinary approach in diagnosis and therapy is mandatory.
               
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