Highlights • Rectal GIST is a rare disease, and have often grown by the time of discovery due to lack of initially subjective symptoms.• A large rectal GIST often require… Click to show full abstract
Highlights • Rectal GIST is a rare disease, and have often grown by the time of discovery due to lack of initially subjective symptoms.• A large rectal GIST often require extensive surgery which may lead to postoperative bowel dysfunction.• Preoperative chemotherapy with imatinib mesylate is effective for reducing the rectal GIST.• Laparoscopic intersphincteric resection may be a useful technique for giant rectal GIST, which enables anal preservation.
               
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