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Successful free flap salvage surgery with off-label use of Alteplase: A case report, review of the literature and our free flap salvage algorithm

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Highlights • Recombinant tissue-type plasminogen activators help to rescue free flaps; Alteplase.• Alteplase is a successful ultima ratio for venous thrombosis.• Use of Alteplase must be embedded in a salvage… Click to show full abstract

Highlights • Recombinant tissue-type plasminogen activators help to rescue free flaps; Alteplase.• Alteplase is a successful ultima ratio for venous thrombosis.• Use of Alteplase must be embedded in a salvage algorithm.• Salvage algorithm must differentiate between arterial and venous problems.

Keywords: use alteplase; free flap; salvage algorithm; salvage; flap salvage

Journal Title: International Journal of Surgery Case Reports
Year Published: 2020

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